Transform Your Skin with Nanofat and Innovative Treatment Combinationsin Scottsdale, AZ

featured image
May 27, 2025

At Defyne Plastic Surgery, we harness the power of regenerative medicine to restore and rejuvenate your skin using your body’s own healing capabilities. One of our most advanced tools is Nanofat—a highly refined, stem cell-rich substance, derived from your own fat that transforms the tone, texture, and quality of your skin from the inside out.

Nanofat refers to fat that has been emulsified into a smooth, fluid form—rich in adipose-derived stem cells, growth factors, and regenerative elements. Nanofat is used in combination with microneedling, microcoring or Laser treatments to revitalize skin, improve elasticity, soften fine lines, and enhance overall skin tone and texture.

Concepts of Regenerative Aesthetics 

In the field of regenerative aesthetics, triggering the skin’s healing process can be achieved through two different techniques. The first is to create acute injury to the skin to trigger the body’s natural healing process, such as with microneedling, microcoring, and laser treatments. The second is to administer various forms of regenerative topical treatments such as stem cells, exosomes, and PRP to unlock and maximize your body’s healing capability. At Defyne, we utilize a combination of these two techniques to provide the best possible outcomes. 

How is Nanofat Made?

The process begins with a gentle liposuction procedure, where a small amount of fat is harvested from areas like the abdomen, thighs, or flanks. Using advanced technologies such as LipoCube, we then purify and emulsify the fat, isolating the most potent regenerative elements. At Defyne we inject Nanofat directly or apply it topically in a cream base to targeted areas for natural-looking, long-lasting rejuvenation.

How Nanofat Fits in

To stimulate the skin’s natural healing process, we use the latest and most effective technologies, such as 

  • Microneedling
  • The world’s first FDA-approved fiber laser that specifically limits thermal injury and can be used safely on all skin types
  • The world’s first FDA-approved micro-coring technology to reduce the volume and stimulate the quality of skin directly

Secondly, we harvest the nanofat and create a personalized cream that is applied at the time of the treatment and continues over the next few days.  Nanofat increases the speed and the overall effect of healing and continues rejuvenating the area for months to come. This combination provides stunning results with minimal risks or downtime.

In the case of hair restoration, nanofat is directly injected into targeted areas to stimulate hair growth.

Benefits of Nanofat

Nanofat is a powerful rejuvenation tool that is made by your body, for your body, and is able to greatly improve skin quality and achieve natural-looking aesthetic improvements. Benefits of our nanofat procedures include:

Natural Regeneration: Nanofat harnesses the healing power of your body’s own stem cells and growth factors. Nanofat is processed to separate stem cells and growth factors from adipose tissue. These elements are powerful in promoting tissue regeneration, stimulating collagen production, and enhancing the skin’s natural healing mechanisms.

Natural and Biocompatible: Since nanofat is derived from the patient’s own fat, there is no risk of rejection or allergic reaction. This makes it a safe and effective choice for individuals seeking natural rejuvenation.

Long-Lasting Results: Nanofat supports deep skin structure improvement, providing more sustainable rejuvenation.

Minimal Downtime: treatments require little recovery time so that you can get back to your routine quickly.

Enhanced Healing: These treatments promote tissue healing, reduce scars, and improve skin texture for a smoother complexion. The effects keep working for months after treatment to maintain improved skin texture and quality. 

Defyne Procedures that Utilize Nanofat

At Defyne, we utilize the powerful healing components of nanofat in a selection of our Signature Procedures, including: 

ReGen Dermacore

The ReGen Dermacore treatment is designed to specifically stimulate your tissue’s natural healing properties. It involves a combination of micro coring or laser coring with a regenerative component such as nanofat, exosomes, or PRP to achieve comprehensive skin rejuvenation. When Dermacoring is combined with regenerative treatments like PRP, exosomes, or nanofat, the aim is further to enhance skin healing, regeneration, and scar reduction.

ReGen Restore

The ReGen Restore treatment harnesses the regenerative powers of nanofat to restore hair growth. It is particularly effective in addressing thinning hair, a receding hairline, and androgenetic alopecia. By transferring nanofat into the scalp, adipose-derived stem cells work to stimulate hair regrowth for a fuller head of hair. 

ReGen Needling

The ReGen Needling treatment is designed to improve the look and feel of your skin. By combining microneedling with nanofat, PRP, or exosomes, this treatment boosts regenerative outcomes, deeply revitalizing the skin. 

What to Expect with Nanofat

Prepare

The first step toward achieving your rejuvenated complexion is through a consultation with one of our specialized patient care coordinators. During this appointment, you can share your medical history, discuss your aesthetic concerns, and ask any questions you have about treatment. 

During Your Treatment

The exact steps associated with your nanofat treatment may vary depending on the individual techniques used. However, treatment will involve the two popular techniques used in regenerative aesthetics mentioned above to trigger tissue regeneration. These include, first, creating a small injury to the skin to trigger the body’s natural healing process and second, administering various forms of regenerative topical treatments to maximize your body’s healing capability. When employing nanofat, the regenerative components that are derived from your own body’s fat are used to create a cream to boost overall healing.

Downtime & Recovery 

The downtime associated with your nanofat treatment will most likely depend on which procedure it is being combined with. Nanofat does not add any downtime.  Our team will provide you with specific, detailed aftercare instructions to help ensure the best possible outcomes.

Contact Us Today to Learn More 

At Defyne, we are committed to helping you achieve radiant, youthful skin through the latest regenerative technologies. If you want to learn more about our offered nanofat treatments, contact us today to schedule a consultation.

Contact Us

Request a Consultation

If you are ready to take the first step toward defining your destiny and achieving your best look yet? At Defyne, our board-certified plastic surgeons are skilled in performing both surgical and non-surgical procedures, achieving individualized, natural-looking results. Contact Defyne in Scottsdale, AZ, today to schedule your consultation appointment.

https://crm.symplast.com/v2/location/qXFXdyjF2jevgT5XesXp/dashboard